Clinical Trial Recruitment Lab

Clinical Trial Knowledge Hub

Clinical Trial Knowledge Hub

Advancing Alzheimer’s Trials Through Evidence

Improving recruitment and enrollment in Alzheimer’s clinical trials requires a range of evolving strategies. The Knowledge Hub from the USC Clinical Trial Recruitment Lab (CTRL) offers pilot case studies, key insights and evidence-based best practices to make your trials more effective and inclusive.

Our Pilots

CTRL pilots are where ideas are put to the test in the real world. Each project explores practical ways to improve how clinical trials reach, engage and reflect the communities they aim to serve. By examining what works—and what doesn’t—these pilots generate real-world evidence and lessons that can strengthen recruitment practices across the field.

Remote Biomarkers

Can remote blood collection be used to identify potential trial participants?

Recruitment Incentives

Can financial incentives boost enrollment of diverse populations in a memory concerns registry?

Digital Assessments

Can digital tests detect early signs of Alzheimer’s?

EHR Recruitment

Can electronic health record data identify dementia risk and link patients to care?

Cultural Sensitivity

Do culturally tailored recruitment materials improve participation rates?

Community Prescreening

Can community-based group screenings increase enrollment?

AI Assistant

Can an AI-powered voice assistant help older adults decide whether to enroll in trials?

Rural Recruitment

Can AI be used to remotely identify and recruit rural participants into Alzheimer’s trials?

Mobile Testing

Can EHRs and mobile cognitive tests identify engaged trial candidates?

AI-Enabled Recruitment

Can AI-driven EHR tools in primary care improve early detection and recruitment?

Resource Library

Explore expert insights from CTRL and Schaeffer Center researchers, along with best practices from the academic and commercial sectors. Together, these resources ensure the Knowledge Hub reflects rigorous scholarship while offering practical, actionable tools to enroll more and diverse participants in clinical trials.

Our Research & Resources

Access publications and tools from CTRL and Schaeffer Center experts for strengthening recruitment and retention.

Best Practices & Tools

New!

Review open-access resources and best practices, drawing on peer-reviewed literature, tools, expert insights and case studies gathered from a broad range of stakeholders.

African American doctor talking to a senior woman after medical examination at the hospital.

CTRL Symposium

Dec. 1: Breakthroughs to Access — The Future of Alzheimer’s Clinical Trials

The USC Clinical Trial Recruitment Lab (CTRL) is bringing together policymakers, researchers, industry leaders, and patient advocates to explore how Alzheimer’s treatment breakthroughs are changing the clinical trial landscape.