Study Term
2024 – 2026

Status
In progress

Researchers held virtual listening sessions with American Indian and Alaska Native (AI/AN) adults aged 30 and older, recruited online and through an existing registry. Participants shared perspectives on facilitators and barriers to research participation, provided feedback on existing recruitment materials, and guided the development of new culturally tailored resources. Using this input, researchers created a professionally produced recruitment video.

In the second phase, participants were randomized to view either a culturally tailored video or one that was not, with outcomes measured through self-reported surveys and enrollment in an AI/AN-focused research registry. Researchers also measured attitudes toward Alzheimer’s trials, willingness to participate and perceptions of the materials.

Finally, findings were synthesized into a culturally relevant recruitment framework for engagement of AI/AN adults in Alzheimer’s research. The video and framework will be disseminated through professional and community networks.

AI/AN adults were engaged through a combination of interviews and listening sessions. The format fostered open dialogue, generating rich qualitative insights into cultural and community-specific considerations for clinical trial recruitment. Participants reviewed and critiqued existing materials; advised on clarity, relevance, and cultural appropriateness; and suggested adaptations to better resonate with AI/AN audiences. This feedback directly shaped the design and content of the video used in the trial and informed the refinement of the final theoretical framework.