Background
Collection and analysis of prescreening data across sites in a multi-site trial could provide valuable information to improve understanding of recruitment interventions. Researchers developed an electronic data capture system to centrally collect a subsect of prescreening variables before study-wide implementation in the AHEAD 3–45 study.
Collection and analysis of prescreening data across sites in a multi-site trial could provide valuable information to improve understanding of recruitment interventions. Researchers developed an electronic data capture system to centrally collect a subsect of prescreening variables before study-wide implementation in the AHEAD 3–45 study.
Findings
Seven vanguard sites provided prescreening data on 1,029 participants, with number of prescreens varying widely across sites (ranging from 3 to 611). From these preliminary data, researchers found that referrals through websites (including the study website, site website, and ClinicalTrials.gov) accounted for a substantial proportion of prescreens. They also identified early trends suggesting that certain recruitment sources may be more effective for specific racial and ethnic groups.
Citation
Kirn DR, et al. Centralizing prescreening data collection to inform data-driven approaches to clinical trial recruitment. Alzheimers Res Ther. 2023 May 2;15(1):88. doi: 10.1186/s13195-023-01235-4.
The study is available at Alzheimer’s Research & Therapy.
*Content last updated September 2026
