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Peer-Reviewed Literature

Community Engagement in Diverse Populations for Alzheimer’s Disease Prevention Trials

Background

Racial and ethnic minority groups are often underrepresented in Alzheimer’s disease prevention research. Researchers at Duke University in Durham, North Carolina, used a community engagement approach to build a registry of healthy adults age 55 and older who were interested in future prevention studies.  

Findings

The registry enrolled 2,311 volunteers, approximately 31% of whom were African American and 74% were women. Among the recruitment strategies tested, community engagement was the most effective for building a large, diverse pool of potential participants. However, trial eligibility criteria may limit the participation of African American volunteers.

Citation

Romero H.R., Welsh-Bohmer K.A., Gwyther L.P., et al. Community engagement in diverse populations for Alzheimer disease prevention trials. Alzheimer Dis Assoc Disord (2014) 28(3):269-74. doi: 10.1097/WAD.0000000000000029

The study is available at Alzheimer Disease & Associated Disorders.

*Content last updated September 2026