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Clinical Trial Knowledge Hub

Using Web-based Cognitive Assessments to Boost Engagement

Clinical Trial Knowledge Hub

CTRL Pilot
Using Web-Based Cognitive Assessments
to Boost Engagement

Research Focus

Can a novel, easy-to-use online cognitive test increase ongoing engagement with a memory concerns registry, especially among underrepresented groups?

Study Term
2022 – 2026

Status
In progress


Pilot Description

A novel, self-administered online memory assessment known as the Multiday Boston Remote Assessment for Neurocognitive Health (BRANCH) was tested in an existing online research registry of older adults (APT Webstudy). Each BRANCH test session takes approximately 12 minutes, and when the same tests are taken over multiple days, BRANCH learning curves can detect early decline in learning and memory for people at higher risk of future Alzheimer’s diagnosis.

Initial studies evaluated user experience with BRANCH, including how enjoyable and challenging users perceived the tests, before it was integrated into the APT Webstudy platform. Researchers then compared completion rates for BRANCH with a previous APT Webstudy assessment. Two invitations for BRANCH participation were sent six months apart, allowing for evaluation of initial engagement and sustained interest over time.


Participant Input

A brief user experience survey was conducted online following completion of the BRANCH test series. Each user was surveyed about basic demographic characteristics, testing environment, problems encountered and level of “enjoyability” and “challenge” for each test. Survey feedback was carefully reviewed and informed decisions around optimization of BRANCH when incorporated into the APT Webstudy platform.


Key Lessons

Online testing works
It is feasible to gather cognitive data remotely from diverse older adults in an online research registry using BRANCH.

Users support it
Feedback shows participants liked BRANCH, found it appropriately challenging and enjoyed it more over time.

Repeat engagement
First-day BRANCH completion rate was over 20% higher than the cognitive test used previously in the APT Webstudy. Over 80% of users completed at least 3 of 5 BRANCH test days, the minimum number to yield meaningful data.


Lead Researchers

Doris Molina-Henry